Symbol
Name
ID

Nlrp1b
NLR family, pyrin domain containing 1B
MGI:3582959

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

myocarditis

increased macrophage apoptosis

pancreas inflammation

enlarged spleen

increased neutrophil cell number

increased dendritic cell number

decreased B-1 B cell number

decreased B-1b cell number

decreased B-2 B cell number

decreased B cell number

decreased NK cell number

decreased central memory CD8 positive, alpha-beta T cell number

increased effector memory CD8-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

decreased single-positive T cell number

decreased lymphocyte cell number

decreased macrophage cell number

increased IgE level

abnormal macrophage physiology

increased macrophage cytokine production

decreased interleukin-1 alpha secretion

decreased interleukin-1 beta secretion

increased tumor necrosis factor secretion

increased inflammatory response

meningitis

liver inflammation

lung inflammation

Availability

Mouse Genotype

Nlrp1a^m1Btlr/Nlrp1a^m1Btlr

Nlrp1a^m2Btlr/Nlrp1a^m2Btlr

Nlrp1a^Neut1/Nlrp1a^Neut1

Nlrp1b^tm1Bhk/Nlrp1b^tm1Bhk

Nlrp1a^Neut1/Nlrp1a⁺

Tg(Nlrp1b)1Die/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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